factors that predict where miRNA binds include adenine and urasil-rich sequences, as well as the distance of target sites away from the center of long UTR's. Prior to this Hot Paper, researchers knew ...

MicroRNAs work by binding to complementary target sites ... Recently, researchers have begun to exploit endogenous miRNA regulation to target the expression of exogenously delivered genes and ...

Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

In this interview, industry expert Dr. Lohit Khera discusses the evolving role of microRNA in research, diagnostics, and ...

Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

Thus, animal miRNAs tend to regulate large target cohorts. Paradoxically ... For example, our studies identified transcription factors, RNA binding proteins, and signaling genes as critical miRNA ...

Dental caries (tooth decay) is a common oral health condition that often causes significant pain and discomfort and may even ...

and the constitution and activity of such complexes could be specified by sequence-specific binding proteins that recognize parts of the microRNA (Fig. 2b, bottom). It will be important to ...

Researchers show that glycoRNAs, uncovered by the lab of Nobel Laureate, Carolyn Bertozzi, can be used to fight cancer.

A new University of Cincinnati Cancer Center study has identified a particular strand of microRNA as a promising new target for overcoming breast cancer treatment resistance and improving outcomes.

While mRNA vaccines represent a transformative platform for infectious disease control, their efficacy in antigen-presenting cells (APCs) remains vulnerable to endogenous regulatory networks, ...