Kelsey Grammer says that he drank, used drugs, and engaged in 'fairly exotic sexual behavior' to cope with the horrific murder of his sister Karen in 1975: 'A lot of fun and then the fun ran out.'

Kelsey Grammer is opening up about the 1975 murder of his sister, Karen Grammer, in his new book "Karen: A Brother Remembers."

Kelsey Grammer has struggled with the loss of his sister, Karen Grammer, for decades. But now, the Cheers alum is opening up about his late sibling and honoring her in his 2025 book, Karen: A Brother Remembers. In the member, the actor takes readers through his childhood and the aftermath of Karen’s death.