When Grey's Anatomy took off as a cultural phenomenon in the mid-2000s, Patrick Dempsey's Dr. Derek Shepherd also swiftly became one of the biggest heartthrobs on television. Nicknamed "McDreamy ...

Kate Walsh played Derek Shepherd's ex-wife, Dr. Addison Montgomery, on the series from 2005-2012 Georgia Slater is a staff editor on the Parents team at PEOPLE. She has been working at PEOPLE ...

Ellen Pompeo and Patrick Dempsey costarred as Meredith Grey and Derek Shepherd on Grey’s Anatomy until Dempsey’s exit in 2015 Ellen Pompeo and Patrick Dempsey are reminiscing on one of the ...

Throughout the medical drama's run, Meredith Grey has mainly lived in two homes: the childhood home she inherited, with a constant rotation of roommates, and the dream house Derek Shepherd built ...