Xavier and colleagues collected tissue from the small intestine epithelium of mice and built transcriptional profiles using RNAseq. One of the striking revelations was the discovery of new subtypes of ...

requiring constant and precise regulation of intestinal stem cells (ISCs) to sustain the production of new absorptive enterocytes and secretory cells, including Paneth, goblet, tuft, and ...

Most of the body's immune cells are found in the connective tissues of the small intestines, just beneath the epithelium. Tuft cells and receptors in the villi trigger an immune response to infection.