requiring constant and precise regulation of intestinal stem cells (ISCs) to sustain the production of new absorptive enterocytes and secretory cells, including Paneth, goblet, tuft, and ...

Xavier and colleagues collected tissue from the small intestine epithelium of mice and built transcriptional profiles using RNAseq. One of the striking revelations was the discovery of new subtypes of ...

Tuft cells act as regenerative stem cells in the human intestine Hubrecht Institute Journal Nature Funder China Scholarship Council, ZonMw, Dutch Lung Fund, EMBO, Netherlands Organ-on-Chip ...

"The intestine has ... regular intestinal cells back into regenerative stem cells, Brumbaugh says. Using animal models, he, Dempsey, and the rest of their research team found that H3K36 ...