Negative selection in fetal thymus clonally deletes many self-reactive T cells, permanently removing ... factor regulating genes implicated in Treg development was confirmed.

Researchers have uncovered a surprising mechanism by which a single genetic mutation in the BCL11B gene causes both immune dysfunction and brain development issues.

The thymus produces T cells, which help the body to fight infection ... research say their findings could be significant in the development of immune-boosting therapies for over-60s and those ...

Data now show that thymus-derived self-peptide-specific ... sites for B7H3 cell surface localization and T cell inhibition, followed by the development of N91/309 and N104/322 preferentially ...

The thymus gland is part of our lymphatic system. It’s involved in the development of a type of white blood cell called a T lymphocyte. These white blood cells are part of your immune system. They ...

T cells are produced in the thymus, a specialized organ of the immune system. During development, Treg cells are trained to recognize specific peptides, including self-peptides from the body.

He uses mouse models to study the thymus, the organ in which specialized immune cells called T cells mature. His goal is to apply his findings to develop new therapies to promote immunity in cancer ...