Ubiquitous as pharmaceutical intermediates, ketones and esters are widely used for the synthesis of drug molecules. Yet both share a critical limitation: Generally, only two specific sites within ...

Garner, R., Schafer, D. J., Watkins, W. B., and Young, G. T., Peptides, Proc. Ninth Europ. Peptide Symp., Orsay (edit. by Bricas, E.), 145 (North-Holland, Amsterdam ...

greatly simplifying the synthesis process. In the Claisen reaction, two molecules combine to form a larger intermediate compound, which is then converted into the desired ester in the retro ...

THE synthesis of new cytostatic drugs is governed by the attempt to find new substances which unite maximum therapeutic effectiveness with minimum toxicity. For this purpose it seems to be ...