spironolactone, triamterene). The primary risk of eplerenone is hyperkalemia (which can cause serious arrhythmias). Periodic monitoring of potassium levels is recommended for patients at risk of ...

In a multicenter, 8-week trial in 417 essential hypertensive patients eplerenone 50, 100, or 400 mg o.d. or 25, 50 or 200 mg b.i.d. was compared with spironolactone 50 mg b.i.d. or placebo.

With spironolactone (Aldactone) treatment for acne rising several-fold in recent decades, safety concerns persist for this off-label practice in understudied populations. A database of U.S. insurance ...

Spironolactone was initiated at a dose of ... with the use of more-selective agents, such as eplerenone, and studies on these selective agents should be conducted accordingly.

Jolly presented the spironolactone arm of the 2x2 factorial ... Over 2 decades ago, the aldosterone antagonist eplerenone proved beneficial after MI complicated by left ventricular dysfunction ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...