Somatic mutations take place in non-reproductive cells. Many kinds of somatic mutations have no obvious effect on an organism, because genetically normal body cells are able to compensate for the ...

Researchers make hiPSCs by harvesting somatic cells—often from skin—from a person and then reprogramming them to enter an embryonic-like state. Nik-Zainal says that she and her colleagues were clued ...

Somatic mutations are those that are acquired during the formation of cancer and are not present at birth. They cannot be passed down to children and are present only in the cells affected by cancer.

As we age, our cells slowly accumulate random mutations in their genes, many of which are harmless. These are known as ...

Researchers using next-generation DNA sequencing have identified four specific genes whose mutations are linked to the ...

created an NIH3T3 fibroblast cell line expressing a tetracycline-regulated ... The type of AID-induced mutations resembled those of somatic hypermutation of immunoglobulin ...

A major new study has revealed that the genes we inherit at birth play a much larger role in cancer than previously ...

Also, DNA repair mechanisms are able to mend most changes before they become permanent mutations, and many organisms have mechanisms for eliminating otherwise permanently mutated somatic cells.

In cancer, one of the leading causes of death in the US, cells divide wildly out of control. Can tumor suppressor genes and proto-oncogenes provide clues on how to stop this process? Aa Aa Aa ...

QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced a series of product and partnership updates designed ...