Somatic mutations are those that are acquired during the formation of cancer and are not present at birth. They cannot be passed down to children and are present only in the cells affected by cancer.

Somatic mutations take place in non-reproductive cells. Many kinds of somatic mutations have no obvious effect on an organism, because genetically normal body cells are able to compensate for the ...

A major new study has revealed that the genes we inherit at birth play a much larger role in cancer than previously ...

Researchers make hiPSCs by harvesting somatic cells—often from skin—from a person and then reprogramming them to enter an embryonic-like state. Nik-Zainal says that she and her colleagues were clued ...

As we age, our cells slowly accumulate random mutations in their genes, many of which are harmless. These are known as ...

Also, DNA repair mechanisms are able to mend most changes before they become permanent mutations, and many organisms have mechanisms for eliminating otherwise permanently mutated somatic cells.

created an NIH3T3 fibroblast cell line expressing a tetracycline-regulated ... The type of AID-induced mutations resembled those of somatic hypermutation of immunoglobulin ...

In cancer, one of the leading causes of death in the US, cells divide wildly out of control. Can tumor suppressor genes and proto-oncogenes provide clues on how to stop this process? Aa Aa Aa ...