Why is knowing the atomic structure of molecules useful? Learn why, and how information like this about protein structure is shared through a publicly available database.

Sickle cell conditions are genetic blood disorders that affect haemoglobin, the molecule in red blood cells responsible for carrying oxygen throughout the body. While both sickle cell trait and ...

Novo Nordisk has doubled down on position in the sickle cell disease (SCD ... and result from abnormal production or structure of haemoglobin in red blood cells. Etavopivat is an oral selective ...

More information: Ambroise Wonkam et al, FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries, Nature Communications (2025). DOI: 10.1038 ...

Background Sickle cell trait (SCT) is considered a benign heterozygous carrier state (both normal haemoglobin and abnormal HbS) compatible with elite level sport, whereas the autosomal recessive state ...

The abnormal haemoglobin (HbS), causes red blood cells to change their structure and become like ... To be born with sickle cell disease, a child has to inherit a copy of the sickle cell gene ...

Sickle cell disease is a genetic blood disorder characterised by the presence of abnormal haemoglobin (Hb ... and economic deprivation have on brain structure. This may lead to treatments ...

SCD affects many parts of the body, and is associated with severe painful crises. People with sickle-cell anaemia have a type of haemoglobin (called haemoglobin S (HbS) or sickle haemoglobin) which ...

Sickle-cell anaemia is also referred to as "HbSS", "SS disease", "haemoglobin S" or permutations thereof. In heterozygous people, who have only one sickle gene and one normal adult haemoglobin ...

A new drug called Voxelotor which alleviates the symptoms of sickle cell disease has been described as "life-changing". It works by helping haemoglobin hold on to more oxygen and prevent them from ...