Oddsmakers project the San Francisco 49ers (6-10) to put up a fight in their attempt to break their three-game losing streak, as they are just 4.5-point underdogs in a matchup with the Arizona

Head coach Kyle Shanahan told reporters Thursday that Purdy will not play Week 18 against the Arizona Cardinals. Purdy suffered a right elbow contusion with nerve inflammation in San Francisco's 40-34 loss to the Detroit Lions on "Monday Night Football."

One player who should be healthy after not showing up on the practice participation report is wide receiver Jauan Jennings. Jennings has been the breakout star of the 2024 season for the 49ers, and now with one week to go he’s just 77 yards shy of his first-career 1,000-yard season.

San Francisco 49ers quarterback Brock Purdy suffered a right elbow contusion with nerve inflammation in Monday night's loss to the Detroit Lions, head coach Kyle Shanahan said Tuesday. Although it

San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to one score.

The San Francisco 49ers officially ruled out QB Brock Purdy from Week 18 due to an elbow injury, per Nick Wagoner. San Francisco also ruled out WR Deebo Samuel (ribs, wrist), OL Spencer Burford (calf),