In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule with enzymatic properties. The catalytic center of the ribosome, known as the peptidyl transferase center (PTC), is ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

including ribosomal RNA (rRNA), transfer RNA (tRNA) or small nuclear RNA (snRNA). Organisms display non-uniform transcriptional variability in response to genetic and environmental perturbations.

Ribosomal RNA (rRNA) is a component of the ribosomes, the cellular machinery responsible for protein synthesis. rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and ...

Translation is the process by which a protein is synthesized from the information contained in a molecule of messenger RNA (mRNA). During translation, an mRNA sequence is read using the genetic ...

A new review article highlights the transformative role of circular RNA (circRNA ... recent discoveries demonstrate that specific internal ribosome entry sites (IRES) and N6-methyladenosine ...

The research field of "cellular IRESes" lay dormant for decades, as there was no uniform standard of reliable methods for the ...