to "barcode" ribosomal RNA (rRNA) inside living cells. By writing genetic information directly into the 16S rRNA—a molecule ...

Part of the problem is that, once a patient starts taking the medication, clinicians can’t tell when the bacteria has been ... the TB bacterium’s 16S ribosomal RNA (rRNA) as a sensitive ...

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent ...

For instance, bacteria contain a single type of RNA ... RNA pol I transcribes ribosomal RNAs (rRNAs), RNA pol II transcribes RNAs that will become messenger RNAs (mRNAs) and also small regulatory ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA ... dominant in bacteria, RNAP (green) can interact with ribosomal protein ...

In bacterial cells, cold shock proteins (CSPs ... between the nascent peptide and amino acid residues in the ribosomal RNA, leading to a rearrangement in RF2, shifting it to an inactive conformation.

The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall ... This discovery led to the concept of the ribosome as a ribozyme, an RNA molecule with ...

Ribosomal RNA (rRNA) is a component of the ribosomes, the cellular machinery responsible for protein synthesis. rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and ...