These molecules induce the sequence-specific silencing of genes by the process of RNA interference (RNAi) in a variety of organisms, including humans.
CHICAGO — Lepodisiran, a small interfering RNA agent, lowered lipoprotein(a) levels at 180 days, with a reduction of more ...
Rebecca Roberts is a science writer and communicator. She earned her PhD in molecular biology from the University of the Sunshine Coast in Australia and completed a two-year postdoctoral fellowship at ...
The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...
The inability to deliver therapeutic RNA molecules to cell types beyond the liver is holding back the progress of RNA medicine, but Sixfold Bioscience has a solution. The company has engineered ...
Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...