outlining cutting-edge research that is identifying new miRNA targets. He’ll also discuss the latest methodologies in miRNA research, including next-generation sequencing and miRNA inhibition.
By treating imMKCLs with a miRNA let-7a-5p inhibitor, the research team observed significant upregulation of immune-related genes, such as PF4, PPBP, ISG15, and IFIT3, in the let-7 low imMKCL cell ...
Depending on the degree of complementarity between the miRNA and its mRNA target, the interaction leads to either inhibition of translation or degradation of the mRNA. It is estimated that miRNAs ...