Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene ...

Such gene signatures, however ... Most commercially available technologies for global miRNA expression profiling are based on DNA microarrays, in which the probes are spotted onto a glass surface.

Figure 1: Using microRNA target sites to target transgene and viral expression. Gene and cell therapy. We first showed that endogenous miRNA regulation can be used to improve vector control when ...

miRNA Discovery Phase PBMC miRNA expression was assessed by small RNA sequencing, using pools of equal amounts (1 µg) of RNA from PDAC patients (n = 20), those with benign pancreatic disease ...

During graduate school, he saw an opportunity to merge his expertise in miRNA with his lifelong interest in butterflies ... “I thought these miRNAs would be minor regulators of gene expression—maybe ...

They also have microRNAs (miRNA), or small non-coding RNAs that help with gene expression. According to the study, miRNA from plants can be absorbed through food. With this information ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to ...

miRNAs are important negative gene regulators that have critical roles ... The evaluated study examined the miRNA profiles in peripheral blood mononuclear cells from PDAC patients.