The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...

These likely represent blood precursors of pathogenic tissue macrophages. This work is important, because it not only defines a new monocyte cell taxonomy relevant for RA—with 11 continuous cell ...

In work recently published in Arteriosclerosis ... a macrophage-focused therapy could take different forms—cell therapy delivering the anti-inflammatory macrophages themselves, delivery of ...

M1 macrophages accumulate at the tumor and exert antitumor activity. Researchers have attempted to use them in adoptive cell therapies, but these cell therapies are in their early stages with limited ...

The cell and drug components give MDCs a dual mechanism-of-action that combines direct cancer-cell killing and immune activation. Macrophages are ideal for getting ferritin cages to cancer cells.

Research identifies how viral respiratory infection damages macrophages and suggests treatment with a pre-existing FDA approved drug.