The most important game of the 2025 season so far for Lionel Messi and Inter Miami is Wednesday night's Concacaf Champions Cup meeting with LAFC.

Inter Miami and LAFC face off in the first leg of the Concacaf Champions Cup quarterfinals. Here’s everything we know about Lionel Messi's availability for the game.

Lionel Messi traveled to Los Angeles with Inter Miami and will likely play against LAFC in the Concacaf Champions Cup quarterfinals first leg.

Miami will travel to Los Angeles for the first leg of the quarterfinals, with four MLS teams vying to break Mexico's streak

The CONCACAF Champions Cup tournament has reached the quarterfinals, and Wednesday night will see LAFC and Inter Miami face off for Leg 1 of the competition (they’ll play again next Wednesday too). Whichever team wins the two clashes will face either the Vancouver Whitecaps FC or Pumas UNAM in the semis.

Any time a Miami team faces an L.A. team, it is bound to be a glitzy affair with celebrity spectators, and this one is no exception. The sport’s biggest star, Inter Miami captain Lionel Messi, draws crowds wherever he goes.