Currently antibiotic prophylaxis administered to a woman during labour is the main means of preventing GBS disease in newborn infants, but only if the bacterium is detected during pregnancy.

Thus, while it appears that treatment of bacterial vaginosis reduces rates of pPROM, no effects were noted with antibiotic therapy for GBS prophylaxis in the setting of premature labor with intact ...

Gestation at <37 weeks, duration of membrane rupture of ≥18 hours, or temperature of ≥100.4 ºF (≥38.0 ºC) are clinical indications for intrapartum prophylaxis if the GBS status is unknown ...