The genetic information stored in DNA is a living archive of instructions ... being expressed in a cell at a particular point in time. Ribosomes are the sites in a cell in which protein synthesis ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The ...

RNA polymerase enzymes read the DNA sequence and synthesize messenger RNA (mRNA) molecules, which carry the genetic information to the ribosomes for protein synthesis. translation is the process by ...

Bin Wu, associate professor in the department of Biophysics and Biophysical Chemistry at the School of Medicine, visited ...

Poxviruses are a family of large, double-stranded DNA viruses ... underlying molecular structure of the ribosome, leading to ...

The process of translation by ribosomes, which functions as a factory of protein synthesis, may be impeded by ‘ribosome ...

The cell creates mRNA, a copy of DNA, to assemble proteins ... aids in the mRNA's unfolding in preparation for translation ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and catalyze the formation of peptide bonds between amino acids during translation. RNA synthesis, or transcription, ...

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...