DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA—the first step of the process by which an organism's ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

Transcription factors are proteins that can bind to DNA and affect the expression of genes; some are known as master regulators that can have a wide impact | Genetics And Genomics ...

Genetically speaking, it's a bacterium's worst-case scenario: During transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While these ...

Old viral DNA, once thought to be gone forever, is reactivated in mammalian embryos, with each species showing unique variations. An atlas of transcription initiation reveals regulatory principles of ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the 'dark side' of the ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...

Andrew Teschendorff, Professor at the Chinese Academy of Sciences, is developing computational systems-biological tools to ...