Researchers have identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in ...

Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School ...

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at ...

A team of researchers has used advanced DNA sequencing to develop the most comprehensive atlas yet of genetic change through ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by ...

An INRS research team has identified a new family of enzymes that can make precise cuts in single-stranded DNA. A few years ...

According to new research next-generation DNA sequencing (NGS) -- the same technology which is powering the development of tailor-made medicines, cancer diagnostics, infectious disease tracking, and ...

Study: Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics. Image Credit: Tatjana Baibakova / Shutterstock A recent study published in the journal ...

Replication stress, frequently observed in rapidly ... such as those that mediate DNA repair and cell-cycle checkpoints, can also contribute to an unstable genome. A gene that encodes an RNA ...