This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Among these mysteries are i-motifs, unusual knot-like DNA structures formed when cytosine-rich sequences fold into a four-stranded, twisted configuration. Recent research has illuminated the ...

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually ...

Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

The cause is related to expansion of repeating DNA units, in which specific strings of genetic code—in this case, a series of cytosine-adenine-guanine nucleotides, or CAG, on one strand of the DNA and ...

IN the nucleic acids, cytosine is connected to a sugar residue through N 1 of the pyrimidine ring. Here we describe the results of an X-ray diffraction analysis of crystals of N 1-methyl cytosine.

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...

The thymine-adenine (T-A) base pair is held together by fewer hydrogen bonds compared to the guanine-cytosine (G-C) base pair, which has three hydrogen bonds. The complementary base pairing in DNA ...

Six of these polymorphisms are single base pair substitutions, although one involves the simple repeat of cytosine residues at nt 311–315. The CRS has five residues in this repeat, whereas most ...