Over the past decade, there have been scattered reports of mammalian cells’ own DNA being found in the cytoplasm, mainly in the context of disease and aging. While it is not unusual to find DNA from ...

A new study in Nature identifies a long-sought cytoplasmic 'sensor' that is responsible, at least in part, for interferon responses induced by double-stranded DNA. How do cells detect non-self ...

When starving conditions are prolonged, cells digest part of their own cytoplasmic components to ... degrade damaged organelles, pathogenic inclusions, or invasive bacteria (Nakatogawa et al.

leaving sister cells connected by a stable cytoplasmic bridge. This bridge between sister cells allows the exchange of ...