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"In the brains of these patients, TDP-43 somehow mislocalizes, accumulates in the cytoplasm where it forms insoluble inclusions, and is depleted from the nucleus." Despite its critical role ...
“In the brains of these patients, TDP-43 somehow mislocalizes, accumulates in the cytoplasm where it forms insoluble inclusions, and is depleted from the nucleus.” Despite its critical ...
“In the brains of these patients, TDP-43 somehow mislocalizes, accumulates in the cytoplasm where it forms insoluble inclusions, and is depleted from the nucleus.” The mechanisms underlying this shift ...
Whereas the former change appears to induce motor neuron destruction by a necrotic-like mechanism, it is unclear whether cytoplasmic inclusions, that cause dysfunction to motor neurons 9 ...
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Protein 'seeds' trigger key pathological features of ALS and frontotemporal dementia"In the brains of these patients, TDP-43 somehow mislocalizes, accumulates in the cytoplasm where it forms insoluble inclusions, and is depleted from the nucleus." Despite its critical role ...
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