For instance, deletions that span a centromere result in an acentric chromosome that will most likely be lost during cell division. As with duplications, deletions can affect gene dosage and thus ...

We present a 7-year-old boy with a long history of multiple ... XXY karyotype with concurrent duplication of 3p21.31 by microarray analysis. Maternal genetic analysis demonstrated the same 3p21.31 ...

Large and rare duplications and deletions in a chromosome region known as ... were identified in 7.4% of early-onset bicuspid ...