Scientists at the University of Geneva (UNIGE) have combined high resolution microscopy and kinematic reconstruction techniques to visualize, in motion, the genesis of the human centriole.
New research points to how these replication processes may be coordinated. Centriole cylinders are made up of nine microtubule triplets, which are attached to each other by a fibrogranular material.
Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles ...
TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...