Deanna earned their PhD in cellular biology from McGill University in 2020 and has a professional background in medical writing. They are an associate science editor at The Scientist. View Full ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

Plant breeding plays a vital role in ensuring global food security by increasing crop yields, improving nutritional quality ...

Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

In a new development, researchers have successfully created an efficient two-line system for hybrid seed production in ...

The recent discovery of CRISPR/Cas9 technology simplified engineering synthetic gene drives for diverse animal species. Nowadays, synthetic gene drives have been engineered in laboratory mosquitoes ...

CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform.

The two main components of the CRISPR/Cas9 system include guide RNA (gRNA ... or nonhomologous end-joining (NHEJ).