Antibiotic resistance is a global concern that threatens ... the Department of Microbiology at Illinois, leveraged the CRISPR-Cas9 system—a highly effective tool for gene editing.

She has since then studied cancer heterogeneity and its consequence on why therapies fail and how tumor cells acquire resistance mechanisms. View Full Profile. Learn about our Editorial Policies.

“The study is a proof of concept that CRISPR/Cas9 can be used to destroy DNA viruses and block viral infection and disease progression,” said Yinong Yang, who studies molecular plant-microbe ...

The research uses the CRISPR-Cas9 genome-editing tool to enhance cassava’s resistance to diseases, tolerance to drought, and starch content. The study identifies and targets critical genes ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

They are using CRISPR-based ... with drug resistance 1. The possibilities of CRISPR screening didn’t stop there. In addition to loss-of-function screens that use Cas9 to inactivate genes ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

CRISPR-Cas9 is not the first method available to scientists for modifying DNA; it is by far, however, the easiest to use. With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA ...