Melanoma study identifies a mechanism for eliminating harmful cells from cancer treatment
After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...
News Medical19d
Study reveals major differences between human and mouse PD-1 in cancer research
Since its discovery in the 1990s, "programmed cell death protein 1," or PD-1, has been regarded as a leading target in cancer treatments. A "checkpoint" receptor that often resides on the surface ...
Scientists unveil surprising human vs mouse differences in a major cancer immunotherapy target
Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is ...
BioTechniques9d
Are mice reliable models for PD-1 studies?
Researchers have discovered that mouse PD-1 is significantly weaker than human PD-1, calling into question their reliability ...
Researchers examine protein arrangement in cell membrane that triggers programmed cell death
As the relevant protein structures are often only 1 to 100 nanometers (nm ... which ultimately leads to controlled or ...
Business Wire1mon
Merck Closes Exclusive Global License Agreement for LM-299, An Investigational Anti-PD-1/VEGF Bispecific Antibody
About LM-299 LM-299 is an investigational bispecific antibody targeting both programmed cell death protein-1 (PD-1) and vascular endothelial growth factor (VEGF). This innovative therapeutic ...
The Pharma Letter6d
With tislelizumab, BeiGene brings immunotherapy to more patients in Europe
This executive interview, sponsored by BeiGene, is with Jan-Henrik Terwey, Vice President, Medical Affairs Europe at BeiGene.
‘Direct link’ found between eating fiber and anti-cancer effects — which foods are best
We know fiber is essential to a healthy and nutritious diet, yet only 7% of Americans eat the recommended daily amount.
Phys.org13d
Scientists create comprehensive map of protein locations within human cells
Spatial organization of proteins (dots) within a human cell: Each protein is placed according ... of proteins involved in a form of programmed cell death called ferroptosis led the researchers ...
Phys.org1mon
Introducing perceptein, a protein-based artificial neural network in living cells
Westlake University in China and the California Institute of Technology have designed a protein-based system ... to stay alive or undergo programmed cell death. Cells naturally process multiple ...